Ellen E Sparger

Ellen E Sparger

Medicine & Epidemiology


Education
1977, DVM, University of Georgia School of Veterinary Medicine, Athens, GA
1983, MS, Michigan State University School of Veterinary Medicine, East Lansing Michigan
1990, PhD, University of California, Davis, Davis, CA
Active Research Grants
Principal Investigator, SIVdeltavif Reservoirs In Vivo, (Principal Investigator), NIH/NIAID
Principal Investigator, Feline Immunodeficiency Virus Orf-A: A Model for HIV Vpr?, (Principal Investigator), NIH/NIAID
Honors and Awards
1980 Phi Zeta Veterinary Honor Society
1984 Diplomate of American College of Veterinary Internal Medicine
1988-1990 Individual National Research Service Award, NIH
Most Recent Five Book Chapters
2005 Sparger EE: FIV as a Model for HIV: An Overview, , Animal Models of HIV Disease and Control, New York. .
1993 Sparger EE: Current thoughts on feline immunodeficiency virus infection, , Veterinary Clinics of North America: Small Animal Practice, Feline Infectious Diseases, Philadelphia, PA. .
1990 Torten M, B Rideout, PA Luciw, EE Sparger and NC Pedersen: Co-infection of cats with feline immunodeficiency virus (FIV) and feline leukemia virus (FeLV) enhances the severity of FIV infection and affects the distribution of FIV DNA in various tissues, Schellekens H and M Horzinek, (ed), Animal Models in Aids, Amsterdam. 209-219.
1990 Torten M, EE Sparger, BA Rideout, NC Pedersen and PA Luciw: Co-infection of cats with FIV and FeLV affects both quantity and distribution of FIV DNA in various tissues, , Vaccines 90, . 375-378.
1990 Sparger EE: Feline immunodeficiency virus, August JR, (ed), Consultations in Feline Internal Medicine, Philadelphia, PA. .
Ten Recent Publications

2009
Dubie RA, Maksaereekul S, Shacklett BL, Lemongello D, Cole KS, Villinger F, Blozis SA, Luciw PA, Sparger EE
Co-immunization with IL-15 enhances cellular immune responses induced by a vif-deleted simian immunodeficiency virus proviral DNA vaccine and confers partial protection against vaginal challenge with SIVmac251

2009
Maksaereekul S, Dubie RA, Shen X, Kieu H, Dean GA, Sparger EE
Vaccination with vif-deleted feline immunodeficiency virus provirus, GM-CSF, and TNF-alpha plasmids preserves global CD4 T lymphocyte function after challenge with FIV

2009
Sparger EE, Gardner MB, Barry PA
Exploiting the natural history of cytomegalovirus to vaccinate against HIV

2008
Sparger EE, Dubie RA, Shacklett BL, Cole KS, Chang WL, Luciw PA
Vaccination of rhesus macaques with a vif-deleted simian immunodeficiency virus proviral DNA vaccine

2007
Shen X, Leutenegger CM, Stefano Cole K, Pedersen NC, Sparger EE
A feline immunodeficiency virus vif-deletion mutant remains attenuated upon infection of newborn kittens

2006
Gupta S, Leutenegger CM, Dean GA, Steckbeck JD, Cole KS, Sparger EE
Vaccination of cats with attenuated feline immunodeficiency virus proviral DNA vaccine expressing gamma interferon

2006
Gupta S, Leutenegger C, Dean G, Sparger EE
Construction and characterization of feline immunodeficiency virus proviral mutants that coexpress interferon gamma and green fluorescent protein

2004
Gemeniano MC, Sawai ET, Sparger EE
Feline immunodeficiency virus Orf-A localizes to the nucleus and induces cell cycle arrest

2003
Gemeniano MC, Sawai ET, Leutenegger CM, Sparger EE
Feline immunodeficiency virus ORF-Ais required for virus particle formation and virus infectivity

2001
Bigornia L, Lockridge KM, Sparger EE
Construction and in vitro characterization of attenuated feline immunodeficiency virus long terminal repeat mutant viruses