Hong Ji

Hong Ji

Associate Professor and Associate Professor in Residence

Anatomy, Physiology & Cell Biology


Education
2002, BS, University of Science and Technology of China, Hefei, China
2007, PhD, Vanderbilt University, Nashville, TN
2011, PostDoctoral Fellow, Johns Hopkins School of Medicine, Baltimore, MD
Active Research Grants
Other, California National Primate Research Center, Jeffery Gibeling (Principal Investigator), NIH
Principal Investigator, Role of TET1 in airway epithelium and childhood asthma, (Principal Investigator), NIH/NIAID
Collaborator, Role of microbiome in neonatal lung maturation and immune susceptibility, Lisa Miller (Principal Investigator), NIH/NIAID
Other, Epigenetic determinants influencing development and evolution of chronic post-surgical pain in children undergoing musculoskeletal surgery, Vidya Chidambaran (Principal Investigator), NIH/NIDA
Other, Linking pre- and post-natal psychosocial determinants, DNA methylation, and early developmental health disparities, Bowers (Principal Investigator), NIH
Co-Investigator, A hypercholesterolemia-induced immunometabolite in atherosclerosis, P. K. Shah (Principal Investigator), NIH
Most Recent Five Book Chapters
2018 Ji H: Chapter 5: Epigenetics and Epigenomic study in asthma, Wang X, Chen Z, (ed), Genomic Approach to Asthma, . .
2016 Oh S, Lin PI, Barzman D, Ji H, Hutton J: Chapter 7: Post-genomic Era in Autistic Spectrum Disorder, , Recent Advances in Autism, . 1-9.
2016 Abdel-Hameed EA, Ji H, Shata MT: Chapter 2: HIV-Induced Epigenetic Alterations in Host Cells, Minarovits J, Niller HH, (ed), Advances in Experimental Medicine and Biology, . 27-38.
Research Focus
My primary area of expertise is in epigenetics, with an emphasis on understanding the etiology of pediatric lung disease. Specifically, I am interested to understand the epigenetic mechanisms underlying heterogeneous disease phenotypes and mediating the impact of environmental exposures.
Specialty Focus
Epigenetics, molecular biology, lung diseases, responses to environmental exposure
Ten Recent Publications

2023
Ji H, Brown AP, Henson SN, Haczku A
The "epiTet" of air pollution: epigenetic regulation of airway inflammation by Tet1.

2022
Zhu T, Brown AP, Cai LP, Quon G, Ji H^
Single-Cell RNA-Seq Analysis Reveals Lung Epithelial Cell Type-Specific Responses to HDM and Regulation by Tet1

2022
Brown AP, Cai L, Laufer BI, Miller LA, LaSalle JM, Ji H^
Long-term effects of wildfire smoke exposure during early life on the nasal epigenome in rhesus macaques

2022
Folger AT, Nidey N, Ding L, Ji H, Yolton K, Ammerman RT, Bowers K
Association Between Maternal Adverse Childhood Experiences and Neonatal SCG5 DNA Methylation-Effect Modification by Prenatal Home Visiting

2021
Bowers K, Ding L, Ji H, Nidey N, Meyer J, Ammerman R, Ginkel JV, Folger A, Yolton K
Pregnancy and Infant Development (PRIDE) - a preliminary observational study of maternal adversity and infant development

2021
Breton C, Landon R, Kahn L, Enlow MB, Peterson A, Bastain T, Braun J, Comstock S, Duarte C, Hipwell A, Ji H, LaSalle J, Miller R, Musci R, Posner J, Schmidt R, Suglia S, Tung I, Weisenberger D, Zhu Y, Fry R
Exploring the evidence for epigenetic regulation of environmental influences on child health across generations

2021
Chidambaran V, Zhang X, Pilipenko V, Chen X, Wronowski B, Geisler K, Martin LJ, Barski A, Weirauch MT, Ji H
Methylation quantitative trait locus analyses of chronic postsurgical pain uncover epigenetic mediators of genetic risk

2020
Delano K, Folger AT, Ding L, Ji H, Yolton K, Ammerman RT, Van Ginkel JB, Bowers K
Associations between maternal community deprivation and infant DNA methylation of the SLC6A4 gene

2020
Zhu T, Zhang X, Chen X, Brown A, Weirauch M, Guilbert T, Hershey G, Myers JB, Ji H^
Nasal DNA methylation differentiates severe from non-severe asthma in African-American children

2020
Zhu T, Li S, Wang J, Liu C, Gao L, Zeng Y, Mao R, Cui B, Ji H^, Chen Z
Induced sputum metabolomic profiles and oxidative stress are associated with chronic obstructive pulmonary disease (COPD) severity: potential use for predictive, preventive and personalized medicine.