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Hong Ji

Hong Ji

Assistant Professor and Assistant Professor in Residence

Anatomy, Physiology & Cell Biology


Education
2002, BS, University of Science and Technology of China, Hefei, China
2007, PhD, Vanderbilt University, Nashville, TN
2011, PostDoctoral Fellow, Johns Hopkins School of Medicine, Baltimore, MD
Active Research Grants
Principal Investigator, Role of TET1 in airway epithelium and childhood asthma, (Principal Investigator), NIH/NIAID
Principal Investigator, Environmental Health Science Scholar Award supported by P30ES023513: Epigenetics as a link between developmental exposures to long-term pulmonary toxicity, (Principal Investigator), NIH/NIEHS
Principal Investigator, Pilot Grant supported by P30ES023513: Genome-wide epigenetic analysis of persistent airway epithelial cell response to wildfire, (Principal Investigator), NIH/NIEHS
Principal Investigator, ALA/AAAAI Allergic Respiratory Diseases Award, DNA methylation, genetic variation, and difficult-to-treat asthma, (Principal Investigator), American Lung Association and American and the American Academy of Allergy, Asthma & Immunology
Other, California National Primate Research Center, Mohapatra (Principal Investigator), NIH
Co-Investigator, Role of microbiome in neonatal lung maturation and immune susceptibility, Miller (Principal Investigator), NIH/NIAID
Other, Epigenetic determinants influencing development and evolution of chronic post-surgical pain in children undergoing musculoskeletal surgery, Chidambaran (Principal Investigator), NIH/NIDA
Other, Linking pre- and post-natal psychosocial determinants, DNA methylation, and early developmental health disparities, Bowers and Folger (Principal Investigator), NIH
Most Recent Five Book Chapters
2018 Ji H : Chapter 3: Epigenetics and Epigenomic study in asthma, , Serial Book: Translational Bioinformatics; Volume Book: “Genomic Approach to Asthma”, . .
2016 Oh S, Lin PI, Barzman D, Ji H, Hutton J : Post-genomic Era in Autistic Spectrum Disorder, , , . .
2015 Abdel-Hameed EA, Ji H, Shata MT : HIV-Induced Epigenetic Alterations in Host Cells. Chapter: Patho-Epigenetics of Infectious Disease, , Advances in Experimental Medicine and Biology, . 27-38.
Research Focus
My primary area of expertise is in epigenetics, with an emphasis on understanding the etiology of pediatric lung disease. Specifically, I am interested to understand the epigenetic mechanisms underlying heterogeneous disease phenotypes and mediating the impact of environmental exposures.
Ten Recent Publications

2019
Burleson JD, Siniard D, Yadagiri VK, Chen X, Weirauch MT, Ruff BP, Brandt EB, Hershey GKK, Ji H^
TET1 contributes to allergic airway inflammation and regulates interferon and aryl hydrocarbon receptor signaling pathways in bronchial epithelial cells

2019
Chidambaran V, Zhang X, Geisler K, Stubbeman BL, Chen X, Weirauch MT, Meller J, Ji H
Enrichment of Genomic Pathways Based on Differential DNA Methylation Associated With Chronic Postsurgical Pain and Anxiety in Children: A Prospective, Pilot Study

2019
Folger A, Ding L, Ji H, Yolton K, Ammerman RT, Van Ginkel J, Bowers K
Neonatal NR3C1 Methylation and Social-Emotional Development at 6 and 18 months of age

2018
Zhang X, Chen X, Weirauch MT, Zhang X, Burleson JD, Brandt EB, Ji H^
Diesel exhaust and house dust mite allergen lead to common changes in the airway methylome and hydroxymethylome

2018
Bowers K, Ding L, Gregory S, Yolton K, Ji H, Meyer J, Ammerman RT, Van Ginkel J, Folger A
Maternal distress and hair cortisol in pregnancy among women with elevated adverse childhood experiences

2018
Ji H, Lin P, Oh S
Genomic/Epigenomic Abnormality in Pediatric Cancer

2018
Zhang X, Biagini Myers JM, Burleson JD, Ulm A, Bryan KS, Chen X, Weirauch MT, Baker TA, Butsch Kovacic MS, Ji H
Nasal DNA methylation is associated with childhood asthma.

2017
Chidambaran V, Zhang X, Martin LJ, Ding L, Weirauch MT, Geisler K, Stubbeman BL, Sadhasivam S, Ji H
DNA methylation at the mu-1 opioid receptor gene (OPRM1) promoter predicts preoperative, acute, and chronic postsurgical pain after spine fusion.

2017
Zhang X, Biagini Myers JM, Yadagiri VK, Ulm A, Chen X, Weirauch MT, Khurana Hershey GK, Ji H
Nasal DNA methylation differentiates corticosteroid treatment response in pediatric asthma: A pilot study.

2016
Abdel-Hameed EA, Ji H, Shata MT
HIV-Induced Epigenetic Alterations in Host Cells.