Hong Ji

Hong Ji

Assistant Professor and Assistant Professor in Residence

Anatomy, Physiology & Cell Biology

2002, BS, University of Science and Technology of China, Hefei, China
2007, PhD, Vanderbilt University, Nashville, TN
2011, PostDoctoral Fellow, Johns Hopkins School of Medicine, Baltimore, MD
Active Research Grants
Principal Investigator, Role of TET1 in airway epithelium and childhood asthma, (Principal Investigator), NIH/NIAID
Principal Investigator, Environmental Health Science Scholar Award supported by P30ES023513: Epigenetics as a link between developmental exposures to long-term pulmonary toxicity, (Principal Investigator), NIH/NIEHS
Principal Investigator, Pilot Grant supported by P30ES023513: Genome-wide epigenetic analysis of persistent airway epithelial cell response to wildfire, (Principal Investigator), NIH/NIEHS
Principal Investigator, ALA/AAAAI Allergic Respiratory Diseases Award, DNA methylation, genetic variation, and difficult-to-treat asthma, (Principal Investigator), American Lung Association and American and the American Academy of Allergy, Asthma & Immunology
Other, California National Primate Research Center, Mohapatra (Principal Investigator), NIH
Co-Investigator, Role of microbiome in neonatal lung maturation and immune susceptibility, Miller (Principal Investigator), NIH/NIAID
Other, Epigenetic determinants influencing development and evolution of chronic post-surgical pain in children undergoing musculoskeletal surgery, Chidambaran (Principal Investigator), NIH/NIDA
Other, Linking pre- and post-natal psychosocial determinants, DNA methylation, and early developmental health disparities, Bowers and Folger (Principal Investigator), NIH
Most Recent Five Book Chapters
2018 Ji H : Chapter 3: Epigenetics and Epigenomic study in asthma, , Serial Book: Translational Bioinformatics; Volume Book: “Genomic Approach to Asthma”, . .
2016 Oh S, Lin PI, Barzman D, Ji H, Hutton J : Post-genomic Era in Autistic Spectrum Disorder, , , . .
2015 Abdel-Hameed EA, Ji H, Shata MT : HIV-Induced Epigenetic Alterations in Host Cells. Chapter: Patho-Epigenetics of Infectious Disease, , Advances in Experimental Medicine and Biology, . 27-38.
Research Focus
My primary area of expertise is in epigenetics, with an emphasis on understanding the etiology of pediatric lung disease. Specifically, I am interested to understand the epigenetic mechanisms underlying heterogeneous disease phenotypes and mediating the impact of environmental exposures.
Ten Recent Publications

Folger A, Ding L, Ji H, Yolton K, Ammerman RT, Van Ginkel J, Bowers K
Neonatal NR3C1 Methylation and Social-Emotional Development at 6 and 18 months of age

Bowers K, Ding L, Gregory S, Yolton K, Ji H, Meyer J, Ammerman RT, Van Ginkel J, Folger A
Maternal distress and hair cortisol in pregnancy among women with elevated adverse childhood experiences

Zhang X, Biagini Myers JM, Burleson JD, Ulm A, Bryan KS, Chen X, Weirauch MT, Baker TA, Butsch Kovacic MS, Ji H
Nasal DNA methylation is associated with childhood asthma.

Chidambaran V, Zhang X, Martin LJ, Ding L, Weirauch MT, Geisler K, Stubbeman BL, Sadhasivam S, Ji H
DNA methylation at the mu-1 opioid receptor gene (OPRM1) promoter predicts preoperative, acute, and chronic postsurgical pain after spine fusion.

Zhang X, Biagini Myers JM, Yadagiri VK, Ulm A, Chen X, Weirauch MT, Khurana Hershey GK, Ji H
Nasal DNA methylation differentiates corticosteroid treatment response in pediatric asthma: A pilot study.

Abdel-Hameed EA, Ji H, Shata MT
HIV-Induced Epigenetic Alterations in Host Cells.