Lark L A Coffey

Lark L A Coffey

Associate Professor

Pathology, Microbiology & Immunology

1 Shields Ave, Davis, CA 95616

UC Davis Biomedical and Engineering Entrepreneurship Academy Graduate
2000, B.S., University of the South, Sewanee, Tennessee
2005, Ph.D., University of Texas Medical Branch, Galveston, Texas
2011, , Institut Pasteur, Paris, France
2013, , Blood Systems Research Institute/University of California San Francisco, California, San Francisco, California
2018, , University of California, Davis, Davis, California
Active Research Grants
Principal Investigator, Engineering high fidelity mutations to increase safety of live-attenuated alphavirus vaccines , (Principal Investigator), NIH NIAID
Co-Investigator, Characterization of blood transfusion-transmission of Zika virus in macaques, Mike Busch, Blood Systems Research Institute/UCSF (Principal Investigator), NIH NHLBI extension of Recipient Epidemiology and Donor Evaluation Study-III
Co-Investigator, Macaque model of Zika virus infection, Koen Van Rompay (Principal Investigator), NIH NIAID
Co-Investigator, Pacific Southwest Regional Center of Excellence for Vector-Borne Disease Research at the University of California, Chris Barker, PMI, William Walton, UC Riverside (Principal Investigator), Centers for Disease Control Regional Centers of Excellence
Co-Principal Investigator, Chikungunya virus like particle vaccine development: non-human primate studies to establish correlates of protection, Koen Van Rompay, California National Primate Research Center (Principal Investigator), FDA via PaxVax, Inc.
Co-Investigator, Cognitive, affective, and social development following fetal Zika virus infection of rhesus macaques. Percentile: 4, Eliza-Bliss Moreau, UC Davis (Principal Investigator), NIH NICHD
Principal Investigator, Viral molecular determinants of pathogenic mosquito-borne virus emergence: Usutu virus in Europe and St. Louis encephalitis virus in California, (Principal Investigator), Zoetis UCD2
Principal Investigator, Influenza A virus surveillance in avians and marine mammals in California, (Principal Investigator), NIH NIAID Center for Excellence in Influenza Virus Research
Honors and Awards
2002 Bodhan Nechay Academic Scholarship;
University of Texas Medical Branch, Galveston, TX
2005 Zhou Sisters Academic Scholarship, University of Texas Medical Branch, Galveston, TX
2005-2008 Philippe Foundation International Scholar, Institut Pasteur, Paris, France
2007-2009 Sigma Xi Scientific Honor Society
Most Recent Five Book Chapters
2016 Coffey L : The Nature of Viruses, MacLachlan, NJ, Dubai, EJ, (ed), Fenner’s Veterinary Virology, London. 13-16.
2016 Coffey LL, Weaver SC, Forrester N : Alphavirus Evolution, , Alphaviruses: Molecular Biology, Pathogenesis and Host Interactions, . 21-26.
2016 Forrester NL, Gutierrez S, Coffey LL : The Evolution and Transmission of Vector-Borne Viruses, Weaver, Denison, Roossinck, Vignuzzi, (ed), Virus Evolution: Current Research and Future Directions, . 61-100.
2015 Tsetsarkin K, Coffey LL, Weaver SC : Interaction of Chikungunya virus with the mosquito vector, , Chikungunya Virus, . 99-126.
2008 Coffey LL : Togaviruses not associated with human disease, Mahy B, Van Regenmortel M, (ed), Encyclopedia of Virology, 3rd Edition, Oxford. 91-6.
Research Focus

<strong>Mosquito-borne virus ecology, evolution and emergence</strong>My research seeks to<span><span> understand patterns of viral molecular evolution and the viral genetic factors that promote</span></span><span><span> </span></span><span><span>mosquito-borne virus</span></span><span><span> </span></span><span><span>emergence and disease.</span></span>

Specialty Focus

Genetics of mosquito-borne virusesTransmission dynamics of mosquito-borne virusesSurveillance of mosquito-borne virusesAlphaviruses, flavivirusesRNA virus evolution