Lisa A Miller


Anatomy, Physiology & Cell Biology

CNPRC, Davis, CA 95616

1986, BS, University of California, Davis
1992, PhD, University of California, Davis
1993, PhD, University of California, Davis
1995, PhD, Stanford University School of Medicine, Palo Alto, CA
1997, PhD, University of California, Davis
Active Research Grants
Co-Investigator, California National Primate Center Base Grant, Prasant Mohapatra (Principal Investigator), NIH
Co-Investigator, Epithelial Stem Cells as Repair Agents in Diffuse Alveolar Damage, Harold Chapman, PhD (contact PI) (Principal Investigator), NIH
Principal Investigator, Novel Use of Human iPSC Derived Airway Progenitor Cells to Measure E-cigarette Toxicity, (Principal Investigator), Tobacco Related Disease Research Program
Principal Investigator, Chonic Bleomycin Induced Lung Fibrosis with Cell Transplant, (Principal Investigator), Genentech
Principal Investigator, Health Impacts of California Wildfire PM2.5 Across the Lifespan, (Principal Investigator), California Air Resources Board
Principal Investigator, Supplement, (Principal Investigator), NIH
Principal Investigator, Role of Microbiome in Neonatal Lung Maturation and Immune Susceptibility, (Principal Investigator), NIH
Trainer, California National Primate Research Center Diversity Fellowship, Prasant Mohapatra (Principal Investigator), NIH
Most Recent Five Book Chapters
2022 Royer C, Miller LA, Haczku A: A Novel Nonhuman Primate Model of Nonatopic Asthma, , Methods Mol Biol, . 83-94.
2014 Crowley CM, Miller LA: Chapter 10: Ontogeny of the Pulmonary Immune System, Pinkerton K, Harding R, (ed), The Lung: Development, Aging, and the Environment, 2nd Edition, London, UK. 211-219.
2008 Plopper CG, Smiley-Jewell SM, Miller LA, Fanucchi MV, Evans MJ, Buckpitt AR, Avdalovic M, Gershwin LJ, Joad JP, Kajekar R, Larson S, Pinkerton KE, Van Winkle LS, Schelegle ES, Pieczarka EM, Wu R, Hyde DM: Chapter 54: Primate models of allergic asthma, Bousquet J, Kay AB, Holt PG, Kaplan AP, (ed), Allergy and Allergic Diseases, 2nd Edition, London. 1187-1201.
2008 Hyde DM, Miller LA, Schelegle ES, Fanucchi MV, Van Winkle LS, Tyler NK, Avdalovic MV, Evans MJ, Kajekar R, Buckpitt AR, Pinkerton KE, Joad JP, Gershwin LJ, Wu R, Plopper CG: Chapter 17: Chronic airway disease in nonhuman primates, Voelkel NF, MacNee W, (ed), Chronic Obstructive Lung Diseases, Volume 2, Hamilton. 235-268.
2003 Miller LA: Ontogeny of the Pulmonary Immune System, R. Harding, K. Pinkerton, C. Plopper, (ed), The Lung: Development, Aging and the Environment, London, U.K. .
Research Focus
Lung development, developmental immunology, respiratory toxicology, immunotoxicology, pediatric lung diseases including asthma and infection
Specialty Focus
Anatomy, Immunology, Pulmonary, Nonhuman Primate
Ten Recent Publications

Toth A, Steinmeyer S, Kannan P, Gray J, Jackson CM, Mukherjee S, Demmert M, Sheak JR, Benson D, Kitzmiller J, Wayman JA, Presicce P, Cates C, Rubin R, Chetal K, Du Y, Miao Y, Gu M, Guo M, Kalinichenko VV, Kallapur SG, Miraldi ER, Xu Y, Swarr D, Lewkowich I, Salomonis N, Miller L, Sucre JS, Whitsett JA, Chougnet CA, Jobe AH, Deshmukh H, Zacharias WJ
Inflammatory blockade prevents injury to the developing pulmonary gas exchange surface in preterm primates

Jackson CM, Demmert M, Mukherjee S, Isaacs T, Thompson R, Chastain C, Gray J, Senthamaraikannan P, Presicce P, Chetal K, Salomonis N, Miller LA, Jobe AH, Kallapur SG, Zacharias WJ, Lewkowich IP, Deshmukh H, Chougnet CA
A potent myeloid response is rapidly activated in the lungs of premature Rhesus macaques exposed to intra-uterine inflammation

Kadur Lakshminarasimha Murthy P, Sontake V, Tata A, Kobayashi Y, Macadlo L, Okuda K, Conchola AS, Nakano S, Gregory S, Miller LA, Spence JR, Engelhardt JF, Boucher RC, Rock JR, Randell SH, Tata PR
Human distal lung maps and lineage hierarchies reveal a bipotent progenitor

Stevens J, Steinmeyer S, Bonfield M, Peterson L, Wang T, Gray J, Lewkowich I, Xu Y, Du Y, Guo M, Wynn JL, Zacharias W, Salomonis N, Miller L, Chougnet C, O'Connor DH, Deshmukh H
The balance between protective and pathogenic immune responses to pneumonia in the neonatal lung is enforced by gut microbiota

Schmidt AF, Schnell DJ, Eaton KP, Chetal K, Kannan PS, Miller LA, Chougnet CA, Swarr DT, Jobe AH, Salomonis N, Kamath-Rayne BD
Fetal maturation revealed by amniotic fluid cell-free transcriptome in rhesus macaques

Langel SN, Garrido C, Phan C, Travieso T, Kirshner H, DeMarco T, Ma ZM, Reader JR, Olstad KJ, Sammak RL, Shaan Lakshmanappa Y, Roh JW, Watanabe J, Usachenko J, Immareddy R, Pollard R, Iyer SS, Permar S, Miller LA, Van Rompay KKA, Blasi M
Dam-Infant Rhesus Macaque Pairs to Dissect Age-Dependent Responses to SARS-CoV-2 Infection

Gu C, Upchurch K, Horton J, Wiest M, Zurawski S, Millard M, Kane RR, Joo H, Miller LA, Oh S
Dectin-1 Controls TSLP-Induced Th2 Response by Regulating STAT3, STAT6, and p50-RelB Activities in Dendritic Cells

Cappelletti M, Presicce P, Feiyang M, Senthamaraikannan P, Miller LA, Pellegrini M, Sim MS, Jobe AH, Divanovic S, Way SS, Chougnet CA, Kallapur SG
The induction of preterm labor in rhesus macaques is determined by the strength of immune response to intrauterine infection