Coronavirus Information

Marcelo J. Kuroda

Marcelo J. Kuroda

Professor and Professor in Residence

Anatomy, Physiology & Cell Biology
Center for Comparative Medicine


Active Research Grants
Principal Investigator, Effects of Opioids on SIV Reservoirs in Brain Macrophages of Rhesus Macaques, (Principal Investigator), NIH/NIDA
Principal Investigator, Role of macrophages in lung disease pathogenesis in pediatric AIDS, (Principal Investigator), NIH/NIHLBI
Principal Investigator, Targeting Macrophage Reservoirs in the Macaque Model of Pediatric AIDS, (Principal Investigator), NIH/NIAID
Principal Investigator, Targeting HIV Lung Reservoir in the Macaque Model, (Principal Investigator), NIH/NIAID
Principal Investigator, Macrophages in the pathogenesis of AIDS, (Principal Investigator), NIH/NIAD
Co-Investigator, Center for Experimental Infectious Diseases, Veazey RS (Principal Investigator), NIH/NIGMS
Other, Targeting Brain Macrophage Reservoirs of Infection in Pediatric NeuroAIDS, Kim W-K (Principal Investigator), NIH/ NIMH
Other, Targeting Brain Macrophage Reservoirs of SIV during HAART, Kim W-K (Principal Investigator), NIH/ NIMH
Co-Investigator, Rhesus macaque model of accelerated aging, Didier E (Principal Investigator), NIH/NIA
Co-Principal Investigator, Role of Macrophages in the reactivation of Latent TB during TB/AIDS co-infection, PI (Principal Investigator),
Co-Investigator, Nonhuman Primate Core Cellular Immunology Laboratory for AIDS Vaccine Research and Development, Kaur A (Principal Investigator), NIH/NIAID
Co-Principal Investigator, Targeting Macrophages in Aging SIV-Infected Rhesus Macaques, Didier E (Principal Investigator), NIH/NIA
Most Recent Five Book Chapters
1998 Letvin NL, Yasutomi Y, Shen L, Reimann KA, Chen ZW, Schmitz JE, Kuroda MJ
: The CD8+ T lymphocyte response during primary SIVmac infection, Gupta S, Sher A, Ahmed R, (ed), Mechanisms of lymphocyte activation and immune, New York. .
Ten Recent Publications

2017
Merino KM, Allers C, Didier ES, Kuroda MJ
Role of Monocyte/Macrophages during HIV/SIV Infection in Adult and Pediatric Acquired Immune Deficiency Syndrome.

2017
Fujino M, Sato H, Okamura T, Uda A, Takeda S, Ahmed N, Shichino S, Shiino T, Saito Y, Watanabe S, Sugimoto C, Kuroda MJ, Ato M, Nagai Y, Izumo S, Matsushima K, Miyazawa M, Ansari AA, Villinger F, Mori K
Simian Immunodeficiency Virus Targeting of CXCR3+ CD4+ T Cells in Secondary Lymphoid Organs Is Associated with Robust CXCL10 Expression in Monocyte/Macrophage Subsets.

2017
Sugimoto C, Merino KM, Hasegawa A, Wang X, Alvarez XA, Wakao H, Mori K, Kim WK, Veazey RS, Didier ES, Kuroda MJ
Critical Role for Monocytes/Macrophages in Rapid Progression to AIDS in Pediatric Simian Immunodeficiency Virus-Infected Rhesus Macaques.

2016
Didier ES, MacLean AG, Mohan M, Didier PJ, Lackner AA, Kuroda MJ
Contributions of Nonhuman Primates to Research on Aging.

2016
Filipowicz AR, McGary CM, Holder GE, Lindgren AA, Johnson EM, Sugimoto C, Kuroda MJ, Kim WK
Proliferation of Perivascular Macrophages Contributes to the Development of Encephalitic Lesions in HIV-Infected Humans and in SIV-Infected Macaques.

2016
Foreman TW, Mehra S, LoBato DN, Malek A, Alvarez X, Golden NA, Bucsan AN, Didier PJ, Doyle-Meyers LA, Russell-Lodrigue KE, Roy CJ, Blanchard J, Kuroda MJ, Lackner AA, Chan J, Khader SA, Jacobs WR, Kaushal D
CD4+ T-cell-independent mechanisms suppress reactivation of latent tuberculosis in a macaque model of HIV coinfection.

2016
Lee M, Kim WK, Kuroda MJ, Pal R, Chung HK
Development of real-time PCR for quantitation of simian immunodeficiency virus 2-LTR circles.

2015
Breed MW, Elser SE, Torben W, Jordan AP, Aye PP, Midkiff C, Schiro F, Sugimoto C, Alvarez-Hernandez X, Blair RV, Somasunderam A, Utay NS, Kuroda MJ, Pahar B, Wiseman RW, O'Connor DH, LaBranche CC, Montefiori DC, Marsh M, Li Y, Piatak M, Lifson JD, Keele BF, Fultz PN, Lackner AA, Hoxie JA
Elite Control, Gut CD4 T Cell Sparing, and Enhanced Mucosal T Cell Responses in Macaca nemestrina Infected by a Simian Immunodeficiency Virus Lacking a gp41 Trafficking Motif.

2015
Cai Y, Sugimoto C, Arainga M, Midkiff CC, Liu DX, Alvarez X, Lackner AA, Kim WK, Didier ES, Kuroda MJ
Preferential Destruction of Interstitial Macrophages over Alveolar Macrophages as a Cause of Pulmonary Disease in Simian Immunodeficiency Virus-Infected Rhesus Macaques.

2015
Cai Y, Sugimoto C, Liu DX, Midkiff CC, Alvarez X, Lackner AA, Kim WK, Didier ES, Kuroda MJ
Increased monocyte turnover is associated with interstitial macrophage accumulation and pulmonary tissue damage in SIV-infected rhesus macaques.