Melanie Gareau

Melanie Gareau

Professor

Anatomy, Physiology & Cell Biology


Education
2011, The Hospital for Sick Children, Toronto, Ontario, Canada
2006, PhD, McMaster University, Hamilton, Ontario, Canada
2001, BS, McGill University, Montreal, Quebec, Canada
Active Research Grants
Trainer, Post-baccalaureate research education program at UC Davis, Daniel Starr (Principal Investigator), NIH
Co-Investigator, Coordination of mucosal immune response to enteric bacterial pathogens by nociceptive innervation, Colin Reardon (Principal Investigator), NIH - NIAID
Principal Investigator, The microbiote gut brain axis in Angelman Syndrome, (Principal Investigator), FAST - Foundation for Angelman Syndrome Therapeutics
Co-Investigator, Wound infection impact on microbiota-skin-brain axis, Rivkah Isseroff (Principal Investigator), UC Davis SOM - Dermatology Seed Grant
Principal Investigator, The microbiota gut brain axis in long-COVID, (Principal Investigator), UC Davis SOM
External Links
Gareau Lab
Honors and Awards
2004 Crohn's and Colitis Foundation of Canada student prize
2005 Crohn's and Colitis Foundation of America travel award
2005 Johnson and Johnson summer internship
2005 Ontario Graduate Scholarship in Science and Technology doctoral award
2006 Restracomp Post-doctoral Fellowship, Hospital for Sick Children
2006 Institut Rosell Probiotic Challenge Poster competition
2007-2010 Canadian Institutes of Health Research/Crohn’s and Colitis Foundation of Canada/Institute Rosell Fellowship, (3 yrs)
2007-2009 Canadian Institutes of Health Research/Canadian Association of Gastroenterology/Crohn’s and Colitis Foundation of Canada Fellowship, (2 yrs)
2008 ASM Beneficial Microbes travel award
2008 University of Toronto, Department of Medicine, Gastroenterology Research Day Poster prize
2009 VTEC2009 Dr. Carlos Gianantonio Award travel award
2009 Experimental Biology, APS Takeda travel award
2009-2011 Reva Gerstein Graduate Fellowship in Pediatric Psychology Fund, Hospital for Sick Children Research Institute (2yrs)
2010 Journal of Biochemistry poster prize, Experimental Biology
2011 FASEB Summer Research Conference travel award
2016 UC Davis Federation Faculty travel award
2016 American Physiological Society travel award
2017 UC Davis Federation Faculty travel award
2017 FASEB Travel Award
2018 Journal of Physiology
Editorial board fellowship
2018 American Physiological Society
Gastrointestinal and Liver Physiology
New Investigator Award
2023 Chancellor’s Fellow Award (The program was established in 2000 to honor the achievements of outstanding faculty members early in their careers. Awarded for quality and significance of research and teaching.)
Most Recent Five Book Chapters
2021 Kim HJD, Rude K, Gareau MG^: Chapter 2: Development of the microbiota-gut-brain axis in early life, , Gut-Brain Connection, Myth or Reality?, . 23-47.
2018 Gareau MG, Reardon C, Barrett KE, Sherman PM: Impact of probiotics on communication between the brain-gut: Implications for the treatment of the psychological effects of digestive disease states, Colin Martin and Derek Larkin, (ed), Probiotics in Mental Health, . 29-41.
2016 Gareau MG: Gut Microbiome and Behavior; Cognition and the Microbiome, , International Review of Neurobiology, . 227-246.
2016 Huynh K, Schneider M, Gareau MG: Altering the gut microbiome for cognitive benefit, , The Gut Brain Axis: Dietary, Probiotic, and Prebiotic Interventions on the Microbiota, . 317-330.
2014 Gareau MG: Chapter 16: Microbiota-gut-brain axis and cognitive function, Lyte M, Cryan JF, (ed), Microbial Endocrinology: The Microbiota-Gut-Brain Axis in Health and Disease, . 357-71.
Research Focus
My research focus is on the development of the microbiota-gut-brain axis in the context of neonatal dysbiosis of the gut microbiota.
Specialty Focus
My lab has a specialty focus in microbiology, physiology, immunology, neuroscience and behavior
Ten Recent Publications

2023
Gareau MG, Barrett KE
Role of the microbiota-gut-brain axis in postacute COVID syndrome

2023
Beitnere U, Vilanova-Cuevas B, Christian SG, Taylor C, Berg EL, Copping NA, Dindot SV, Silverman JL, Gareau MG^, Segal DJ
Unique Features of the Gut Microbiome Characterized in Animal Models of Angelman Syndrome.

2022
Gareau MG
The Microbiota-Gut-Brain Axis in Sepsis-Associated Encephalopathy.

2021
Fregoso DR, Hadian Y, Gallegos AC, Degovics D, Maaga J, Keogh CE, Kletenik I, Gareau MG^, Isseroff RR
Skin-brain axis signaling mediates behavioral changes after skin wounding.

2021
Keogh CE, Rude KM, Gareau MG^
Role of pattern recognition receptors and the microbiota in neurological disorders.

2021
Barboza M, Solakyildirim K, Knotts TA, Luke J, Gareau MG, Raybould HE, Lebrilla CB
Region-Specific Cell Membrane N-Glycome of Functional Mouse Brain Areas Revealed by nanoLC-MS Analysis.

2021
Fart F, Salihovic S, McGlinchey A, Gareau MG, Oresic M, Halfvarson J, Hyotylainen T, Schoultz I
Perfluoroalkyl substances are increased in patients with late-onset ulcerative colitis and induce intestinal barrier defects ex vivo in murine intestinal tissue.

2021
Hennessey C, Keogh CE, Barboza M, Brust-Mascher I, Knotts TA, Sladek JA, Pusceddu MM, Stokes P, Rabasa G, Honeycutt M, Walsh O, Nichols R, Reardon C, Gareau MG^
Neonatal Enteropathogenic Escherichia coli Infection Disrupts Microbiota-Gut-Brain Axis Signaling.

2021
Keogh CE, Kim DHJ, Pusceddu MM, Knotts TA, Rabasa G, Sladek JA, Hsieh MT, Honeycutt M, Brust-Mascher I, Barboza M, Gareau MG^
Myelin as a regulator of development of the microbiota-gut-brain axis.

2021
Heskett CW, Teafatiller T, Hennessey C, Gareau MG, Marchant JS, Said HM, Subramanian VS
Enteropathogenic Escherichia coli Infection Inhibits Intestinal Ascorbic Acid Uptake via Dysregulation of Its Transporter Expression.