Stefan Keller

Stefan Keller

Associate Professor

Pathology, Microbiology & Immunology


Licenses
Diplomate of the European College of Veterinary Pathologists
College of Veterinarians of Ontario – Academic license #63569
Education
2003, DVM, University of Berlin, Germany,
2007, Dr. med. vet., University of Zurich, Switzerland,
2015, PhD, University of California, Davis,
Active Research Grants
Principal Investigator, Creating the infrastructure to integrate artificial intelligence into clinical decision-making , (Principal Investigator), Center for Equine Health (CEH), Davis, CA
Principal Investigator, Machine supported interpretation of laboratory data from diseased horses using unsupervised learning, (Principal Investigator), Center for Equine Health (CEH), Davis, CA
Collaborator, Functional analysis of canine non-conventional TCRaß+ CD4-CD8a- double- negative T cells , M. Eschke (Principal Investigator), DFG - German Research Foundation
Principal Investigator, Predicting early treatment failure in feline nasal lymphoma treated with radiation therapy, (Principal Investigator), Center for Companion Animal Health (CCAH), Davis, CA
Most Recent Five Book Chapters
2022 Deravi N, Keller SM, Bienzle D: Chapter 72, T-Cell Tumors, Brooks MB, Harr KE, Seelig DM, Wardrop KJ, Weiss DJ, (ed), Schalm's Veterinary Hematology, 7th Edition, . 605-625.
Research Focus
Lymphoproliferative diseases and adaptive immunity; the composition and dynamics of lymphocyte antigen receptor repertoires in physiologic and pathologic conditions in various species; diagnostic applications of antigen receptor repertoires; combining histopathology and high-throughput methods to understand and diagnose lymphoproliferative diseases.
Specialty Focus
Lymphocyte antigen receptor repertoires, lymphoproliferative diseases, lymphoma, adaptive immunity, anatomic pathology
Ten Recent Publications

2022
Windsor R, Stewart S, Schmidt J, Mosqueda M, Piras I, Keller SM, Steinmetz B, Borjesson DL, Huentelman M, Khanna C
A potential early clinical phenotype of necrotizing meningoencephalitis in genetically at-risk pug dogs.

2021
Windsor R, Stewart SD, Talboom J, Lewis C, Naymik M, Piras IS, Keller S, Borjesson DL, Clark G, Khanna C, Huentelman M
Leukocyte and cytokine variables in asymptomatic Pugs at genetic risk of necrotizing meningoencephalitis

2021
Lee GKC, Bienzle D, Keller SM, Hwang MH, Darzentas N, Chang H, Rätsep E, Egan R, Beeler-Marfisi J
Use of immune repertoire sequencing to resolve discordant microscopic and immunochemical findings in a case of T cell-rich large B cell lymphoma in a young dog.

2021
Radtanakatikanon A, Moore PF, Keller SM, Vernau W
Novel clonality assays for T cell lymphoma in cats targeting the T cell receptor beta, T cell receptor delta, and T cell receptor gamma loci.

2020
Radtanakatikanon A, Keller SM, Darzentas N, Moore PF, Folch G, Nguefack Ngoune V, Lefranc MP, Vernau W
Topology and expressed repertoire of the Felis catus T cell receptor loci

2019
Craig KKL, Wood GA, Keller SM, Mutsaers AJ, Wood RD
MicroRNA profiling in canine multicentric lymphoma.

2019
Hwang MH, Darzentas N, Bienzle D, Moore PF, Guscetti F, Morrison J, Keller SM^
A review of canine B cell clonality assays and primer set optimization using large-scale repertoire data

2019
Le K, Beaufrere H, Laniesse D, Blois S, Kabakchiev C, Smith DA, Finck C, Chalmers H, Brochu N, Keller S, Gaitero L
Diagnosis and long-term management of blastomycosis in two ferrets (Mustela putorius furo)

2019
Matsuyama A, Bienzle D, Richardson D, Deravi N, Hwang MH, Darzentas N, Keller SM^
Composite lymphoma of concurrent T zone lymphoma and large cell B cell lymphoma in a dog

2018
Noland EL, Keller SM, Kiupel M
Subcutaneous Panniculitis-Like T-cell Lymphoma in Dogs: Morphologic and Immunohistochemical Classification