Boaz Arzi, DVM, DAVDC, EVDC

Oral and Maxillofacial Research

(See also: Diagnostic Imaging, Pathology/Virology, Surgery/Emergency and Critical Care)

My current research fields are 1) regenerating the mandibular bone after resective surgery or due to defect non-unions. This project combines the use of BMP-2 and a scaffold and efforts towards understanding stem-cells recruitments locally and systemically 2) adipose-derived mesanchymal stem cells for the treatment of feline gingivostomatitis. 3) the biomechanics and kinematics of mandibular reconstruction in dogs and cats 4) Temporomandibular joint (TMJ) disorders, diagnistics and treatments studies. These projects extend and bridge the clinical practice at the UC Davis VMTH on one side and basic and regenerative laboratory science on the other side.

The summer STAR project is intended to take place at UC Davis.

The 2019 summer STAR project is entitled “Cone Beam Computed Tomography (CBCT) and pathology of canine temporomandibular joint osteoarthritis: an agreement study” and will be done with collaboration with Dr. Derek Cissell.

Please visit Dr. Arzi’s website at: http://www.vetmed.ucdavis.edu/vorl/research-programs/oral-maxillofacial-regeneration/index.cfm


Bruce Hammock

Department of Entomology & UCD Comprehensive Cancer Center
Director, NIEHS-UCD Superfund Research Program
PI, NIH Biotechnology Training Program

(See also: Arthritis/Degenerative Disease, Anesthesia/Pain Management, Food Animal Medicine, Pharmacology)

Dr. Hammock’s laboratory has a long collaboration with faculty and students in the school of veterinary medicine.  His laboratory develops mass spectral and biosensor analytical methods for environmental contaminants and drugs in companion animals.  The laboratory is working on a new branch of the arachidonic acid cascade and is developing drugs to block arthritic and laminitic inflammation in horses and inflammatory and post surgical pain in dogs and cats associated with injury, diabetes, age and other criteria.

Projects:

Use of inhibitors of the soluble epoxide hydrolase to potential treat disease in companion animals such as dogs and cats as well as horses and livestock species.

Pharmacokinetic analysis in development of novel pharmaceuticals for veterinary use.

Fundamental mechanism of action of regulatory lipids.

Natural food additives to expand the efficacy of omega 3 fatty acid supplements in food of companion animal and livestock species.

Development of CNS acting drugs to treat disorders such as Parkinson's and Alzheimer's disease and depression.

See   http://www.biopestlab.ucdavis.edu/ for additional information.


Frank J.M. Verstraete, DrMed Vet, MMed Vet, DAVDC, DECVS, DEVDC

VM: Surgical and Radiological Sciences

Comparative oral anatomy, pathology, diagnostic imaging and surgery

My primary research interest is comparative oral pathology: the study of oral and dental diseases, as well as temporomandibular joint problems, in various species, including the similarities and differences in nature and occurrence of these diseases.

The examination of mammalian skull collections for dental and temporomandibular lesions is an established method of determining the nature and prevalence of oral pathology in a particular species. If performed correctly, such studies can reveal valuable information pertaining not only to the dental diseases occurring in the species, but also to systemic diseases, diet, and behavior. Such studies may also contribute to the understanding of oral diseases in related domestic species.

The California Academy of Sciences in San Francisco and the University of California - Berkeley house a treasure-trove of skulls and are within driving distance from Davis. Their Department of Ornithology and Mammalogy and Museum of Vertebrate Zoology are eager to make their collections available for studies in comparative dental and temporomandibular joint pathology.

Potential projects for STAR Students in 2019 are:

The dental pathology of the Virginia opossum (Didelphis virginiana)
The dental pathology of the coyote (Canis latrans)
The dental pathology of the red fox (Vulpes vulpes)
The dental pathology of the island fox (Urocyon littoralis) – in Los Angeles

 Please visit Dr. Verstraete's website for more information.