In 2015, Izzie, a 6-year-old female yellow Labrador retriever, was a typical active Lab. She loved playing ball, chasing birds, and swimming. When her owners, Morgan and George Birdsong, noticed a tumor growing on her head, they immediately took her to their veterinarian. After diagnosing it as a mast cell tumor, Izzie’s primary veterinarian and a second opinion both offered palliative care as the best option, not giving her very long to live. At this point, Izzie’s tumor had grown to the size of a tennis ball.