Alessandro Venosa

Alessandro Venosa

Associate Professor

Molecular Biosciences


Education
2015, PhD, Rutgers University, Piscataway, NJ
2009, Pharm D, Universita’ degli Studi di Urbino, Italy
Active Research Grants
Principal Investigator, NIEHS, Outstanding New Environmental Scientist Award, (Principal Investigator), Role of Surfactant Protein-C Mutation and Ozone Exposure in the Exacerbation of Pulmonary Fibrosis
Co-Investigator, Understanding the effects of chronic lung injury on the development of early lung cancer, Michelle Mendoza (Principal Investigator), Pilot Grant – Huntsman Cancer Institute, University of Utah
Co-Investigator, Great Salt Lake Dust Pulmonary Health Effects, Christopher Reilly (Principal Investigator), CEPTOR Pilot Grant - Margolis Foundation
Ten Recent Publications

2024
Moos PJ, Cheminant JR, Cowman S, Noll J, Wang Q, Musci T, Venosa A^
Spatial and phenotypic heterogeneity of resident and monocyte-derived macrophages during inflammatory exacerbations leading to pulmonary fibrosis.

2024
Malaviya R, Meshanni JA, Sunil VR, Venosa A, Guo C, Abramova EV, Vayas KN, Jiang C, Cervelli JA, Gow AJ, Laskin JD, Laskin DL
Role of macrophage bioenergetics in N-acetylcysteine-mediated mitigation of lung injury and oxidative stress induced by nitrogen mustard.

2024
Moos P, Cheminant J, Adhikari U, Venosa A^
Transcriptomic-based roadmap to the healthy and ozone-exposed lung.

2023
Warren KJ, Deering-Rice C, Huecksteadt T, Trivedi S, Venosa A, Reilly C, Sanders K, Clayton F, Wyatt TA, Poole JA, Heller NM, Leung D, Paine R
Steady-state estradiol triggers a unique innate immune response to allergen resulting in increased airway resistance.

2022
Nguyen J, Deering-Rice CE, Armstrong BS, Massa C, Reilly CA, Venosa A^
Parenchymal and Inflammatory Cell Responses to Single and Repeated Ozone Exposure in Healthy and Surfactant Protein-C Mutant Lung.

2022
Nguyen J, Armstrong BS, Cowman S, Tomer Y, Veerabhadraiah SR, Beers MF, Venosa A^
Immunophenotyping of Acute Inflammatory Exacerbations of Lung Injury Driven by Mutant Surfactant Protein-C: A Role for Inflammatory Eosinophils.

2022
Golden TN, Venosa A, Gow AJ
Cell Origin and iNOS Function Are Critical to Macrophage Activation Following Acute Lung Injury.

2021
Lam LKM, Murphy S, Kokkinaki D, Venosa A, Sherrill-Mix S, Casu C, Rivella S, Weiner A, Park J, Shin S, Vaughan AE, Hahn BH, Odom John AR, Meyer NJ, Hunter CA, Worthen GS, Mangalmurti NS
DNA binding to TLR9 expressed by red blood cells promotes innate immune activation and anemia.

2021
Tomer Y, Wambach J, Knudsen L, Zhao M, Rodriguez LR, Murthy A, White FV, Venosa A, Katzen J, Ochs M, Hamvas A, Beers MF, Mulugeta S
The common ABCA3E292V variant disrupts AT2 cell quality control and increases susceptibility to lung injury and aberrant remodeling.

2021
Venosa A, Smith LC, Gow AJ, Zarbl H, Laskin JD, Laskin DL
Macrophage activation in the lung during the progression of nitrogen mustard induced injury is associated with histone modifications and altered miRNA expression.