Guillaume de Lartigue

Education

2002, BS, Royal Holloway, University of London, United Kingdom

2007, PhD, University of Liverpool, United Kingdom

Honors and Awards

2006 Best Poster award, Wellcome Trust PhD conference, London

2007 Keystone Symposia Scholarship

2008 Calam Travelling Fellowship

2008 Recipient of the 2008 Burgen Award

2010 Selected to give presentation at the SSAT presidential session at DDW

2012 Selected to attend Little Brain Big Brain conference

2012 Selected by peers to represent the best of Little Brain Big Brain at NGM2012

Most Recent Five Book Chapters

2012 de Lartigue G, Raybould HE.: The Gastrointestinal Tract and Control of Food Intake, Johnson LR, Ghishan FK, Kaunitz JD, Merchant J, Said HM, Wood J, (ed), Physiology of the Gastrointestinal tract, London, UK; Waltham MA, USA; San Diego, CA, USA. 1963-78.

Research Focus

Determining the cellular and molecular mechanisms in vagal afferent neurons involved in the control of feeding behavior, and understanding the role of these neurons in the pathophysiology of obesity using models of diet-induced obesity.

Specialty Focus

Gut-brain signaling; feeding behavior

Ten Recent Publications

2014
Ronveaux CC, de Lartigue G, Raybould HE
Ability of GLP-1 to decrease food intake is dependent on nutritional status

2012
de Lartigue G, Barbier de la Serre C, Espero E, Lee J, Raybould HE
Leptin resistance in vagal afferent neurons inhibits cholecystokinin signaling and satiation in diet induced obese rats

2012
Chichlowski M, de Lartigue G, German JB, Raybould HE, Mills DA
Bifidobacteria isolated from infants and cultured on human milk oligosaccharides affect intestinal epithelial function

2011
de Lartigue G, de La Serre CB, Raybould HE
Vagal afferent neurons in high fat diet-induced obesity; intestinal microflora, gut inflammation and cholecystokinin

2011
de Lartigue G, Barbier de la Serre C, Espero E, Lee J, Raybould HE
Diet-induced obesity leads to the development of leptin resistance in vagal afferent neurons

2011
Lee J, Martin E, Paulino G, de Lartigue G, Raybould HE
Effect of ghrelin receptor antagonist on meal patterns in cholecystokinin type 1 receptor null mice

2010
de Lartigue G, Lur G, Dimaline R, Varro A, Raybould H, Dockray GJ
EGR1 Is a target for cooperative interactions between cholecystokinin and leptin, and inhibition by ghrelin, in vagal afferent neurons

2010
de Lartigue G, Dimaline R, Varro A, Raybould H, De la Serre CB, Dockray GJ
Cocaine- and amphetamine-regulated transcript mediates the actions of cholecystokinin on rat vagal afferent neurons

2008
Burdyga G, de Lartigue G, Raybould HE, Morris R, Dimaline R, Varro A, Thompson DG, Dockray GJ
Cholecystokinin regulates expression of Y2 receptors in vagal afferent neurons serving the stomach