75 Years of Exceptional Care and Innovation | Celebrate with Zoom backgrounds, email signatures and more!

Peter B Ernst

Peter B Ernst

Pathology, Microbiology & Immunology


Licenses
College of Ontario Veterinarians
College of Ontario Veterinarians, Academic License
Association of Medical Laboratory Immunologists
Canadian Society for Clinical Chemists, Elected
Education
1977, BSc, University of Toronto, Toronto, Canada
1981, DVM, University of Guelph, Guelph, Canada
1981, MS, University of Guelph, Guelph, Canada
1985, PhD, McMaster University, Hamilton, Canada
Active Research Grants
Principal Investigator, Mechanisms of apoptotic cell clearance in the human stomach, (Principal Investigator), NIH
Principal Investigator, The role of adenosine receptors in Th cell development and function, (Principal Investigator), NIH
Most Recent Five Book Chapters
2011 Kurtz CC, Wilson JM, Black SG, Ernst PB: Cytokine production by T helper subsets in response to infection and their role in health and disease, Preedy VR, Hunter R, (ed), Cytokines (Modern Insights into Disease from Molecules to Man), Enfield, NH. .
2011 Kurtz CC, Wilson JM, Black SG, Ernst PB: Chapter 7. Cytokine production by T helper subsets in response to infection and their role in health and disease, Preedy VR, Hunter RJ, (ed), Cytokines (Modern Insights into Disease from Molecules to Man), Enfield, NH. 93-106.
2009 Crowe SE, Alam MS, Bhattacharyya A, Ernst PB: Host immunity in the development of gastric preneoplasia, Wang TC, Giraud AS, Fox JG, (ed), The Biology of Gastric Cancer, New York, NY. 425-448.
2006 Ernst PB: The Molecular Mechanisms of Helicobacter pylori Associated Gastroduodenal Disease, Runge MS, Patterson C, (ed), Molecular Medicine, New York. 590-602.
2003 Ernst PB, Ryan K, Goldberg J: What is the exact role of Lewis antigens and autoantibodies in Helicobacter related disease, Hunt RH, Tytgat GNJ, (ed), Helicobacter pylori: Basic mechanisms to clinical cure 2002, Amsterdam. 73-78.
Research Focus
Regulation of gastrointestinal immunity to bacterial infections and the role of engulfment in adenosine production and immune regulation.
Specialty Focus
Add
Ten Recent Publications

2013
Tlaxca JL, Rychak JJ, Ernst PB, Konkalmatt PR, Shevchenko TI, Pizzaro TT, Rivera-Nieves J, Klibanov AL, Lawrence MB
Ultrasound-based molecular imaging and specific gene delivery to mesenteric vasculature by endothelial adhesion molecule targeted microbubbles in a mouse model of Crohn's disease

2013
Mauldin JP, Lu M, Das S, Park D, Ernst PB, Ravichandran KS
A link between the cytoplasmic engulfment protein Elmo1 and the Mediator complex subunit Med31

2012
Luo Y, Kong Q, Yang J, Mitra A, Golden G, Wanda SY, Roland KL, Jensen RV, Ernst PB, Curtiss R
Comparative genome analysis of the high pathogenicity Salmonella Typhimurium strain UK-1

2012
Warren CA, Calabrese GM, Li Y, Pawlowski SW, Figler RA, Rieger J, Ernst PB, Linden J, Guerrant RL
Effects of adenosine A2A receptor activation and alanyl-glutamine in Clostridium difficile toxin-induced ileitis in rabbits and cecitis in mice

2012
Ernst PB, Erickson LD, Loo WM, Scott KG, Wiznerowicz EB, Brown CC, Torres-Velez FJ, Alam MS, Black SG, McDuffie M, Feldman SH, Wallace JL, McKnight GW, Padol IT, Hunt RH, Tung KS
Spontaneous autoimmune gastritis and hypochlorhydria are manifest in the ileitis-prone SAMP1/YitFcs mice

2011
Drygiannakis, I, Ernst, PB, Lowe, D, Glomski, IJ
Immunological alterations mediated by adenosine during host-microbial interactions.

2011
Luo Y, Kong Q, Yang J, Golden G, Wanda SY, Jensen RV, Ernst PB, Curtiss R
Complete genome sequence of the universal killer Salmonella enterica Serovar Typhimurium UK-1 (ATCC 68169)

2011
Ernst PB, Wiznerowicz EB, Feldman SH, Tung KS
Pathogenesis of gastritis in ileitis-prone SAMP1/Yit mice

2011
Das S, Owen KA, Ly KT, Park D, Black SG, Wilson JM, Sifri CD, Ravichandran KS, Ernst PB, Casanova JE
Brain angiogenesis inhibitor 1 (BAI1) is a pattern recognition receptor that mediates macrophage binding and engulfment of Gram-negative bacteria

2011
Wilson JM, Kurtz CC, Black SG, Ross WG, Alam MS, Linden J, Ernst PB
The A2B adenosine receptor promotes Th17 differentiation via stimulation of dendritic cell IL-6