Juvenile Idiopathic Epilepsy (JIE)

Juvenile Idiopathic Epilepsy (JIE)

In collaboration with Dr. Monica Aleman, our lab is investigating the genetic causes of Juvenile Idiopathic Epilepsy (JIE) in Egyptian Arabian foals. JIE is heritable with an autosomal dominant mode of inheritance, yet the genetic cause is unknown. Identifying genetic causes will help to improve strategic breeding programs.

JIE is characterized by seizures in the first year of life in Egyptian Arabian foals. Complications associated with seizures include head injury and aspiration pneumonia. After affected foals reach a year of age, foals do not seizure any longer.  Any lasting problems are often due to head trauma. Definitive diagnosis requires the use of an electroencephalogram.

Are you concerned that your horse may have JIE? Contact our lab for more information on how you can aid in equine genetic research.